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ʬȲټTRPͥδؤ礤(II)ޤ˷ڸ ҥå
2014-4-22 5:37 : monjyu () [ 7880hit ]
üõɸŪTRPͥ롪

ʤɤDz٥󥵡ݤȤƯƤ벹ټTRP(Transient Receptor Potential)ͥϡ㲹ⲹޤǤβٰ򥫥Сݤ10बΤƤޤTRPͥϡ6˦̷Ǥꡢ̾4ޤäơ4Ρ˹Ƥޤٻɷˤ깦륷।ʤɤ˦ή̡䴶οãޤʿ޻ȡˡ42ٰʾ15ٰʲβ٤ˤߤȤ顢βٰdzTRPͥϡˤߤμΤȤƤѤƤ뤳ȤˤʤޤˤߤμΤϿΤƤޤǶTRPͥˤδطܤƤޤˤߤ˴طƤȻפΤϡⲹ󥵡ݤǤTRPV1TRPV3ͥȡ㲹󥵡ݤǤTRPA1TRPM8ͥǤʿ޻ȡˡ
Τ͡ˤߤ˻ȤƤ륢ޤϿ¿ꡢޤ˷ڸϥޤ¿ͤʺѡȤз¥ʡñѡۺѡźѤʤɤδŪʺѤǤԤǤޤȤСǢ¤ʤɤμ¤䳰ʤɤǵо㳲ˤϡ˼Ǥ뤳Ȥ顢õκüTRPͥ뤬ɸŪȤʤäƤޤäơ˼ƤγǤTRPͥľܴؤ礦ޤϡľŪ˷ڸѤȯȻפޤˤߤ˻ȤƤ륢ޤΤTRPͥȴؤ礤ΤƤΤޤ˼ޤ
TRPͥ𤷤˺ѤΥᥫ˥ϡޤ褯ʬäƤޤ󤬡Ūɤ椵Ƥ륫ץ󤬥ҥȤˤʤ뤫⤷ޤ󡣥ץTRPV1ͥʥ˥Ⱥѡˤȡ륷ʤɤΥήǮˤޤǤϲΥץ˺Ѥ򼨤ΤȤȡ³ŪTRPV1ͥγˤꥫ륷बήͥ뵡ǽæ졢ãǤ̡˺ѤȹͤƤޤ
Τˤʤɤ˻ȤƤ륫եݡʥե롢Ǿˤ⡢TRPV1ͥޤʥ˥ȡˤ㲹󥵡TRPA1ͥ˳̡ʥ󥿥˥ȡˤΤƤޤΤ褦TRPͥ˳ˤ˺ѤͤȤˤϡ˥ȡ󥿥˥Ȥξ̤ͤɬפ褦Ǥ
ˤ貹٥󥵡ݤȤƳΤ벼ѡˡʥ2014-4-14ˤˤߤȴطƤΤ϶äǤ⤢ꡢĤμΡʥѥˤʣεǽôʪθΨɤˤ餿ƴޤƱ˥ޤTRPͥ𤷤˻ȤʤΤǤ (by Mashi)  

ʸ: Kamei T. et al.,Novel therapeutic approach to neuropathic pain: Hot and Cool TRP-channel family. Folia Pharmacol. Jpn., 140, 196-200 (2012)
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ټTRPͥȴؤ礦ޤȤʬ
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