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ʬȲټTRPͥδؤ礤(I)ȡݥˤ벼ʤ󤲡˾㳲 ҥå
2014-4-14 9:56 : monjyu () [ 8030hit ]
벼㳲˴ؤ벹ټΤϡ

Υ2014-4-8)ǡȡݥϲټTRP(Transient Receptor Potential)M8ͥ˷礷䴶ȤҤ٤ޤ¤ϤβټTRPͥϡ벼ʤ󤲡˾㳲ȿطޤƱ͡ˤϹⲹ㲹ޤǤβټΤʬۤƤޤ͡ʲ٤ΰ벼ȿͤĴ٤ȡ㲹30ʲˤȹⲹ60ʾˤ벼ȿͤ褯뤳Ȥ顢ټTRPͥΤⲹ󥵡TRPV1TRPV2㲹󥵡TRPM8TRPA14ब벼ȿͤγ˴ͿȹͤƤޤ
Ȥǡ65аʾιԤλ˴ϡ65̤Ȱۤʤꡢٱ꤬˴ξ̤ˤޤƹԤٱΤȾʬʾϸٱȹͤƤޤϷ䡢Ǿɾ㳲ϤȤ͡ʼ¤ˤ벼ȿͤ㲼礭װȤʤäƤޤߤʤɤΤɤ˵ͤޤ餻Τ65аʾιԤʬǤǤϤɤΤ褦ˤ벼㳲ǤΤǤ礦
˽Ҥ٤褦ˡ벼ȿͤˤϹⲹTRPV1TRPV2ͥ롢㲹TRPM8TRPA1ͥ뤬ͿƤΤǡ줾μΤ˷礷ɷ㤹ʤΤѤС벼㳲βԤǤޤޤ˼褦ˡ㲹TRPM8ͥ˷礹ȡݥʥϥåڥѡݥߥȡˡ㲹TRPA1ͥ˷礹륢륤͡ݥȡʥ掠ӤޥݥɡˤʤɤθǤꡢº벼㳲βߤޤޤˤϽ񤤤Ƥޤ󤬡ⲹTRPV1ͥ˷礹륫ץʥȥ饷ˡݻʤɤⲹTRPV1ͥɷ㤷벼ȿͤͶȯޤ
ºݡ벼ȿͤٱ䤷ԤФȡݥϱդ˴ޤߡ벼ȿͤε֤¬ꤹȡȡݥϹԤ㲼벼ȿͤǻٰ¸Ūˤ궯벼ȿͤλ֤ṳ̂ˤȤ𤵤ƤޤʳϷ顢ʸȡˡǶǤϡȡݥΥݤ벼㳲βΤ˻ȤƤޤʥޡʬҤ̳мΤ˷礹ǤϤʤȡݥΤ褦̳мΰʳμΤˤ礷Τ͡Ѥ˱ƶڤܤƤǽޤ (by Mashi)

ʸ: Ebihara T. et al.,Effects of menthol on the triggering of the swallowing relax in elderly patients with dysphagia. Br. J. Clin. Pharmacol., 62, 369-371 (2006)


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