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ݥҡݹҤΤʤ뵻!? ҥå
2019-10-16 7:52 : Mashi () [ 159hit ]

   餺äԻ׵Ĥ˻פäƤ뤳ȤޤƱ褦ʴĶƱ褦ʿ򤷤ƤΤˡ֤ǿιߤϹʤɬפƤʤȤǤΤǤ礦ɤҥȥΥ¸ߤĿͺˤƶڤܤƤ褦Ǥ


   ǯҥȥΥ¸ߤĿͺϡμ¤˴ط뤳Ȥ餫ˤʤĤĤޤȤС륳Ф붯ʤɤΰŪװϡ˥ǥҥɥǥҥɥʡҤ SNPʰ¿ˤ˰¸뤳ȤΤƤޤޤդ˴ͿǥȥP450CYPˤ乳˥ɤդ˴ͿǡиŸǺޥեθ̤˱ƶǤʤɤ⤽ǤΰҤˤιdz˱ƶͿ褦SNPʰ¿ˤȡ̤ȯꡢͭǤջʪѤ줿ꤹ뤳Ȥޤ


   ¤ϤΤ褦ʥΥθĿͺϡμ¤˴طǤʤˤƶͿ뤳Ȥ餫ˤʤĤĤޤȤСҡϿȶʰǤꡢҡݼˤϻղѤϤȤ͡ʷ򹯸̤𤵤Ƥ뤿ᡢǯƿͤоݤ˥ҡݼ̤ȴϢ륲Υΰ褬õƤޤܿͽĤǤϡҡݼ̤ȥΥδطϲƤޤǤ


   Ƕᡢر̿ʳظʤ絬ϰҲϲҤǤҥ󥯥ȤȤζƱǡܿ12ͤΰҾϤ̡ҡݼ٤ˡޤDzƿͽĤƱꤵƤ7ξ7p21ΰ˲äܿͭ12Τ12q24ΰͿƤ뤳Ȥȯޤʿ޻ȡˡ


   ƱǤϡܿ12ͤΥΥWeb󥱡ȾѤƥΥ磻ɴϢ(GWAS:ҥȥΥΤSNPsʰ¿ˤΰҷꤷSNPs٤µŪȤδϢŪĴ٤ˡ)ԤҥȥΥǥҡݼ̤ͭդ˴ϢΤ°̤2ƱꤷޤΤ1ϡҥ7ξ7p21ΰ¸ߤեդ䥳ҡݼ̤ȴϢ뤳Ȥ餫ˤʤäƤAHRҤξή˰֤ƤޤƿͤоݤȤǤAHRҶ˵κ°̤ƱꤵƤꡢܸˤꥳҡݼ̤AHRҤȤδط΢դޤ


   ƿͽĤǤȯƤʤäҥ12Τ12q24ΰκ°̤Ʊꤵޤκ°̤CUX2Ҿ¸ߤƤޤ12q24ΰˤդ˴ؤҤ椷¸ߤƤޤޤҡݼ̤ȴϢƤ°̤ˤĤƾܤϤȡɤκ°̤ˤǯ𺹤ϸޤǤ12q24ΰκ°̤ȥҡݼ̤ȤδϢˤ˽ꡢؤƤޤʿ޻ȡˡ


   եǡʥ2019-7-10ˤ򵯤ҥȤΰҺ°̤ϤɤʤΤǤ礦ޤϹǤϤɤʤΤǤ礦줫ϡҥȥΥȿʤȿδϢˤĤƤޤޤϤʤȻפޤ֤οιߤΰ㤤⡢ҤΤäȤ㤤SNPʰ¿ˤΤʤ뵻ʤΤΤޤ(by Mashi)


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ϪƤ뤦Ĥλ쳤ƻݻҽɡˤĻҤ򿩤٤ƤäפꤪʢDZۤʤƤϡ


ʸHuijuan Jia et al., GWAS of habitual coffee consumption reveals a sex difference in the genetic effect of the 12q24 locus in Japanese populations. BMC Genetics (2019),  DOIֹ10.1186/s12863-019-0763-7
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