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ʬäϷΥȼ̿Ĺӥäˤ륪ݥȥե㲼 ҥå
2019-7-31 7:23 : Mashi () [ 517hit ]

   ȥեȤϡκ˦ιʬʬ򤹤뤷ߤؤ2016ǯΤΡ٥ؾޤޤޤǶǤϸΤϷ̿ˤ⥪ȥեϽפ̤ȤƤޤεǽ¿ĤäƤޤΥαξQQ!?žȯۤ˳ؤֱܴ2017-2-18ˤǤϡ俩䥨ͥ륮ݷ˳ϥݥȥեݤޤ˭٤ʾ֤Ǥϡǡʥ륳ݥ䥢ߥλˤ䥤󥹥ϥݥȥեݤζϤҤȤƯη̿˲ܤȥݥȥեݤ˵ǽΤβդ٤ʤäƤޤȤ򤴾Ҳ𤷤ޤ


   رطϸʤθ楰ݥפϡ饪ȥեƯĥѥ򸫤ĤӥRubicon Run domain beclin-1 interacting and cysteine-rich containing proteinˤ̾դƤޤΥӥϡäͿҥܴκ˦䡢ܾ֤ǻôΤȯޥδκ˦äޤȯɵäôΤϡѥΥӥ뤳Ȥˤꡢ¡Υȥե졢ȴξ㳲뤳Ȥ򤴾Ҳ𤷤ޤʥӥϤ롧ôΤȤʤ륿ѥӥ2017-7-31ˡ


   رطϸʡ԰縦ʤɤθ楰ݥפϡӥ󤬲ȼ祦祦Хޥȿä뤳Ȥ򸫽Фޤ˥ӥȡȥեγȯߤ졢䥷祦祦ХǤϼ̿αĹޤޥǤϲħ뤳Ȥ餫ˤޤη̤顢ӥäϲȼȥե㲼ȸϷװΰĤǤȹͤޤ


   ϷϤʤΤ̿ϤɤΤ褦˷ޤΤޤ褯ʬäƤޤ󤬡ǶθǤϡϷ̿ҤĶˤä椵Ƥ뤳ȤΤƤޤ㤨Х꡼¤䡢󥹥󥷥ʥ˦νʤɤϡưʪμ̿ФȤƤޤθݤϤߤϢޤ󤬡ɤξˤ⥪ȥեȯƤޤޤȥեƯʤ褦ˤưʪǤϡΤ褦ʽ֤򤷤Ƥ̿ϿӤޤ󡣤Ĥޤꡢȥե̿븰򰮤äƤ뤳ȤƤޤ


   ãȼӥȯѲĴ٤Ȥ祦祦Хޥʿ¡¡ˤǡȼӥä뤳Ȥ狼ޤˡRNAˡѤ祦祦ХǥӥԤȡȥեγǧȤȤˡ̿αĹѻޤޤȼ㲼뱿ưǽ졢θȤʤ׶ŽѥѤڸޤ˥ӥεǽ»ΥåȥޥǤϡȼä¡ݲڸƤޤޤޥʤɤǼ̿򿭤ФȤΤƤ륫꡼¤ʤɤν֤Ԥȡӥ㲼뤳Ȥ狼ޤΤ褦ˡȼӥäˤ륪ȥե㲼ȸϷװΰĤȤʤäƤ뤳Ȥޤ(by Mashi)


ͻʿѼ̿Ϥ褽40ȤƤޤĻλ˴¿äΤǡ10ФˤʤФλҶʿ;̿52.4Фˤʤ뤽Ǥ70ФĹ̿äΤǤ礦

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ʸShuhei Nakamura et al., Suppression of autophagic activity by Rubicon is a signature of aging. Nature Communications (2019);10(1):847. doi: 10.1038/s41467-019-08729-6.
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