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2019-3-9 7:01 : Mashi () [ 802hit ]

   ¡ʻǿϳˤϡ̤̾ʻˤʻ٤ƤˤʤɻμµǤ᤭Ĥʤɤλ᤭­ȡȻδ֤˻ʥץ顼ϥХեȤƤФˤޤꡢäƤȻˤʤꡢäƤȻ¤ȤʤꡢϤǽŪ˻򼺤ޤ


   бȤη򹯤ȤϢư뤳ȤܥǤ⤿ӤӤҲ𤷤ƤޤºݡƵ۴ϼǢ¤ʤɤϻ¤ȤδϢΤƤޤ6ǯ˰ٹԤʼĴˤȡܰ¤ȤʤݥåȤ4mmʾ¸ߤƤͤϡ45аʾȾˤãƤꡢºݹԤλ´ԤäƤޤ


   ¤ȶ˻򼺤礭װǤꡢä˹ԤǤϺ縶ǤθݤȤƥȥץȥåߥ塼󥹡Streptococcus mutansˤΤƤޤ¤ˤ¿θݤΤƤꎤǤϥݥեʥ󥸥ХꥹPorphyromonas gingivalisˤȳʤȹͤƤޤ


   ǤϤʤ¤ǻ򼺤ȤˤʤΤǤ礦Ƕᡢرظʤθ楰롼פϡǤ⶯Ϥʻ¸ݥݥեʥ󥸥Хꥹʥ󥸥Хꥹݡˤ˴ȡΥޥȺ˦ʥޥȺ˦˦ˤϡIgE𤷤I륮ȿμΡˤ饤󥿡IL-31Ȥʪʥȥˤ뤳ȤȯޤIL-31ϼ˥إѡT˦黺졢ɤ˴ͿȥԡڤͶȯʪǤ⤢ޤˡˡΥ󥿡-31ϡݻ˦ƱΤǴХꥢ˲¤ΰ˴ؤ뤳Ȥ餫ˤޤ


   ãϡ󥸥ХꥹݤˤޥǥǼ¸ԤФ˥󥸥ХꥹݤȡIL31 mRNAжʤ뤳ȤȯޤޥȺ˦»ޥǤϡ󥸥ХꥹݴǤIL31mRNAжʤϤߤ줺˥ҥȥޥȺ˦˥󥸥ХꥹݤźäȡIL-31λѻޤ


   󥸥Хꥹݤϥ󥸥ѥȤʬǤޤΥ󥸥ѥ󤬥ޥȺ˦ɷ㤷IL31뤳ȤʬޤǴϡ˦֤Υȥ󥯥ΥХꥢˤٶݤοʤɤ˻ߤƤޤޥȺ˦黺줿IL31ϡ˦֤Υȥ󥯥˲뤳Ȥ餫ˤʤޤ


   ޥȺ˦ϡǴˤפɸ˦ǤȿԲʥ륮ݾɾꡢ¤ꤹ褦Ǥ¤ˤɤϡӼθǤ顢ɤ򥳥ȥݥ뤹бѽפȤޤ(by Mashi)


ʸHiroyuki Tada et al., Porphyromonas gingivalis induces the production of interleukin-31 by human mast cells, resulting in dysfunction of the gingival epithelial barrier. Cellular Microbiology (2018)  doi: 10.1111/cmi.12972.
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󥸥ХꥹݤϥޥȺ˦IL-31λͶƳ򤹤
󥸥ХꥹݤϥޥȺ˦IL-31λͶƳ򤹤
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