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2018-9-16 7:23 : Mashi () [ 271hit ]

   ¤μŤѤƤ빳ϡ¤θȹͤƤǾοã(ȥ˥Υ륢ɥʥ)˺Ѥޤβع¤ѵˤäơķϡʹķϡSSRISNRINaSSAʤɤȸƤФ륰롼פʬव졢¿ޤѤƤޤʤ顢ʬʼŸ̤夲ƤȤϤΤοɸŪʬҤ˾ޤƤޤ


   ޤǤˤ⡢´ԤηDZȥ󤬾徺뤳ȡ´ԤǾDZô˦ǤߥꥢǾޥեݥˤƤ뤳Ȥ𤵤ƤޤޤɤؤǡȤдư̮Ųꥦޥꡢ硢ʤɡˤδԤǤϡ¤ʻȯΨ⤤Ȥʤɤ𤵤졢¤ȱɤȤδϢƤޤ¤ȱɤΰ̴طˤ¿ޤ


   ǶᡢذظʤȵذظʤζƱˤꡢȥ쥹ˤޤĤͶƳˡȱַϤˤǾɤפǤ뤳Ȥʬޤ̤ϡ¤֤Ǿɤˤк˦εǽѲפǤ뤳Ȥ򼨺ƤꡢοãϤ˺ѤȤϰۤʤꡢȱʬҤɸŪȤʹγȯˤĤʤǽȻפޤ


   ãϡ¤ΥǥȤơȿҲޥȥ쥹ǥѤޤ¸оݤͺޥˡγʤ̤ͥǹζͺޥ˰10ʬ10Ϣ³˽Ϫȥ쥹Ϳޤȿȥ쥹ˤꡢޥؤϼҲưʤɤΤ͹ư䡢Ǥ԰͹ưжʤͶƳޤιưѲϡߥץߥ SSRI ʤɤιȿͿˤü뤳Ȥ顢ޥΤ¥ǥΰĤȤƤޤ


   ޤȿҲޥȥ쥹ˤǾΰȯѲĴ٤ȤS100 ΰҤȯ徺ƤޤS100ϡǤҲ𤷤褦ˡʥޤȹοͤ2015-4-20ˡ륷ΰǡޥեݥʤɤα˦ƤӴ󤻡Ѥ벽ҤȤΤɤ˴ؤʬҤǤ


   S100ϡȱּΡάΤϥѥ륹2018-7-4ˤǤTollͼΡToll-like receptor; TLRˤΥ֥פǤTLR2 TLR4 뤳ȤΤƤޤʽäS100Ϻ˦ȿ㳲ϢʬҷʥץˤǤ2018-7-4ˡºTLR2/4 »ޥǤϡȿȥ쥹ˤ뤦͹ưʼҲưˤüƤޤ ȿȥ쥹¦ƬʤǾΰǥߥꥢγк˦α塦̤ͶƳޤѲ TLR2/4 »ޥǤϵޤǤ


   ʾη̤顢ȿҲޥȥ쥹ϡȱּTLR2/4 𤷤¦ƬΥߥꥢIL-1TNF ʤɤαȥȯͶƳ𤷤ơк˦α塦̡͹ưͶƳ뤳Ȥ狼ޤώιȤϰäȱʬҤɸŪȤʹγȯԤޤ(by Mashi)


ʸXiang Nie, et al., Innate immune receptors TLR2/4 mediate repeated social defeat stress-induced social avoidance through prefrontal microglial activation. Neuron(2018) https://doi.org/10.1016/j.neuron.2018.06.035[/size]
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