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2018-7-17 9:56 : Mashi () [ 352hit ]

   ǯŻǤǤ˥ݲ̤ʤɤ򸫤뵡̱10ͤ1ͤɥ饤ȸƤޤɥ饤ɻߤɬפޡޱաˤϿǤǤƤΤǤϤʤ¤ϻءءˡءؤλĤؤǷƤޤʿ޻ȡˡܤؤϡպ˦ʬ礵륿ѥΥ¿ޤߡǴ٤ޱդɽ̤ˤȤɤư경ܤޤʬ礵ؤϡؤοʬܤζԤޤǤ⳰¦ˤؤϡޤ֤΢¦Υޥܡʬ礵줿ʥޥХȤޤˤʤꡢޱդξȯɻߡɸ桢ޱդɽĥϤ㲼ʤɤ˽פ̤Ƥޤ


   ˤϿʻޤɽ̤ˤϥХꥢȤüò¸ߤޤޱջؤˤʥޥХˤ⤽Τ褦ʻΰǤꡢޥХμפʹϡ쥹ƥ륨ƥȥåƥȸƤФĹʬҤǤλ¿ϡûúǿ16Ĥ20ġC16-C20ˤǤޥХΥ쥹ƥ륨ƥλûʬȥޥХΥåƥʬΤۤȤɤϡúǿ20İʾC20-C34ǹƤޤ


   Τ褦˥ޥХλûκĹĹȤΤƤޤĹǤ뤳ȤŪյɥ饤ɻߤˤϤ狼äƤޤǤǶᡢ̳ƻرظ污θ楰롼פϡޡޱաλúǺĹûޥĹɥ饤ɻߤ˽פǤ뤳ȤƲޤ


   ãϡûκĹ򿭤ФǡʻûĹǡˤΰĤǤELOVL1ΰҡElovl1ˤɽʳǷ»Υåޥޤΰҷ»ޥϡ֤٤⤯ޱդοʬ̤Ȥɥ饤ξɾ򼨤5Ķޥ¿dz줬ޤΰ۾ϡĹ֤Υɥ饤ˤäƽĤνɤĤ˰줿ȹͤޤ


   ޥΥޥХǤϡúǿC20-C34Υ쥹ƥ륨ƥȥåƥ뤬פǤҷ»ޥǤϤζĹޥХबúǿûΤäƤޤ쥹ƥ륨ƥȥåƥκĹϡʿѤúǿ3ʬƤޤΤ褦˻ûĹELOVL1ĹޥХι˴ͿƤ뤳Ȥ餫ȤʤޤޤޥХबޱեХꥢȤƵǽʥɥ饤ɻߤˤˤϡĹúǺĹפǤ뤳ȤƼޤ


   ɥ饤θ8䤬ؤΰ۾Ǥˤؤ餺ؤ򥿡åȤˤޤϤޤ󡣺󡢶ĹޥХबɥ饤ɻߤ˽פǤ뤳Ȥ餫ȤʤäȤ顢ɥ饤šͽɤ뿷ޤγȯˤĤʤ뤳ȤԤޤ(by Mashi)


ʸTakayuki Sassa et al., Very long-chain tear film lipids produced by fatty acid elongase ELOVL1 prevent dry eye disease in mice. FASEB Journal (2018 Jun) 32(6):2966-2978.  DOI10.1096/fj.201700947R
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