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ĥϥޡ¤˴ؤ륢ߥɦ¤ʬ򤹤Ǥ򥢥ȥȤǿȯ ҥå
2018-5-2 7:30 : Mashi () [ 280hit ]

   ǯäĤĤ륢ĥϥޡ¤ϡǾˤƥߥɦ¿̤˶ŽϷäȤѤƤޤǾ¸ߤк˦ʳκ˦ʥꥢ˦ˤΰĤǤ륢ȥȡ籺˦ˤϡеǽФ͡ʱƶڤܤƤȹͤƤޤĥϥޡ¤ˤ륢ȥȤδؤ礤ˤĤƤϤ褯ʬäƤޤ


   Ƕᡢرطϸʤθ楰롼פϡߥɦ¤ʬ򤹤뿷ǡKLK7ˤȯιǤǾǤϥȥȤʬ礵Ƥ뤳ȡޤĥϥޡ´ԤǾǤϤȯ̤㲼Ƥ뤳Ȥ餫ˤޤ˿ǤΰҤΥåȤǥޥDzϤȤߥɦ¤ʬ򤵤줺Ѥжʤ뤳Ȥʬޤ


   ȥȤϡǾȱ֤ɤĤɤ륰ꥢ˦ΰǡҥȤˤƤϿк˦10ܰʾ¿¸ߤ뤳ȤΤƤޤĥϥޡ´ԤǾǤϥȥȤΰ۾ǧƤޤȿϥߥɦ¤Ѥк˦λФȿȤȤ館ƤꡢȥȤĥϥޡ¤ַΤΤ˿ؤäƤȤϹͤƤޤǤ


   Ƹ楰롼פϡȥȤĥϥޡ¤ˤ륢ߥľܱƶ뤫Ƥ̡ȥȤܾ˥ߥɦ¤ʬ򤹤¸ߤ뤳Ȥ򸫽ФϤη̡KLK7ȸƤФʬ緿ʬǤǽȯޤʿ޻ȡˡ̣Ȥˡܿͤ䲤ƿͤΥĥϥޡ´ԤǾˤKLK7ȯ̤ȾƤ뤳Ȥǧ줿Ȥ顢ʬKLK7ϥĥϥޡ¤ַ˴ͿƤȻפޤ


   ĥϥޡ¥ǥޥǾǤϡߥɦ¤ѤȼʬKLK7ȯ̤äƤ뤳ȤʬޤȥȤ˰Ūʱȿ¿ǻɷ㤷ƤKLK7ȯ̤äޤ󤬡˦Υߥɦ¤äKLK7ȯжʤޤäƥȥȤϡ˦Υߥɦ¤äΤȡʬΤKLK7ȯ徺Ȼפޤǰʤ顢ĥϥޡ´ԤǾǤϲ餫ͳǤȯ徺ʤꤵޤ


   ׾ǻѤƤǧξɤȤơޥʥޥݾˤޤѤȤƤϡãʪǤ륰륿ߥƤNMDAΤФɹѤȹͤƤޤʤä٤ȤˡޥϥȥȤˤ륢ߥɦʬKLK7ȯäʬޤѤ˲äߥɦʬǤȯͶƳ򤹤餷̤ʬäΤǤޤǤ˥ĥϥޡ¤ȯɵˤܤƤʤäȥȤɸŪȤ뤳ȤǡˡͽγȯˤĤʤ뤳ȤԤޤ(by Mashi)

ʸKiwami Kidana et al., Loss of kallikrein-related peptidase 7 exacerbates amyloid pathology in Alzheimer disease model mice. EMBO Molecular Medicine  (2018) 10, e8184 DOI 10.15252/emmm.201708184| Published online 08.01.2018
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