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2018-4-25 7:29 : Mashi () [ 381hit ]

   Ӯưʪǹ٤˿ʲȱַϤǤϡTѵT˦ˤإѡݤ䥭ݵǽʤɤ򼨤BѵB˦ˤΤޤ¿ưʪͭƤ뼫ȱַϤǤϡޥեݥʤɤο˦ſǽȿʤɤôäƤޤȤǯȱַϤƯѵ夬ȯ졢ΥѵϡּѵפΤ褦ˤʤޤ


   ּѵפϥѵϤ°뼫ȱֺ˦Ǥ1233बΤƤޤˤB˦ΤT˦ΤðŪʱϤޤ󡣤ʤ顢κ˦͡ǽȱַϤιݻȿ˽פôäƤꡢ۾ʾˤϥ륮伫ȱּʤɤμ¤θˤʤꤵƤޤޤȯ¿ѵǤ


   ǶᡢرطϸʤظζƱ楰ݥפϡɻ©θȤʤ뼫ѵγᥫ˥餫ˤޤʿ޻ȡˡϡ˼ѵκ˦ɽ̤ȯƤGITR ȸƤФ륿ѥѵγɬܤǤ뤳ȡGITRѥͿ뼫ѵγɻ©θȤʤ롢ȤȯǤ


  ѵκ˦ɽ̤ȯƤGITR (glucocorticoid-induced TNF receptor family-regulated gene) ϡ̷ѥǡTNFʼҡ˼Υѡեߥ꡼°ޤGITRȱֳŪʴƤΰݻ˴ͿƤȹͤƤꡢȱּǥޥˤơGITRγϼʴƤȱּȤƤޤ


   ãϡT˦γ椹뤳ȤΤƤ GITRѥT˦Ȥ̤Υ롼פ°뼫ȱַϤμѵ2ˤ¸ߤ뤳ȡˤ GITRѥ2ѵγɬܤǤ뤳Ȥȯޤ2ѵϡɻ©ʤɤΥ륮Ȥ˺ǽ˳ȱֺ˦Ǥꡢ2ѵ夬ʤȥ륮ʤȤΤƤޤ


   ǡ GITRѥ»ޥǵɻ©ʥ륮©ˤޤˤäͶȯ褦ȤޤGITRѥ»2ѵǤʤ©ޤǤGITR˳ʪȯޥͿȤޤˤ뵤ɻ©ͶȯޤǤ


   ޤޤ褯ʬʤ¿¿ѵǤȯˤäơɻ©뿷Ȥ餫ˤʤޤϡ2ѵ¸ߤ GITRѥ˳ʪõ륮γȯԤޤ(by Mashi)


ʸHiroyuki Nagashima et al., GITR co-signal in ILC2 controls allergic lung. J Allergy Clin Immunol., (2018.Feb.8). pii:S0091-6749(18)30213-6. doi: 10.1016/j.jaci.2018.01.028.
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