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2017-12-28 7:41 : Mashi () [ 716hit ]

   ʬҤǧ̳мΤϡҥȤǤϤ褽400ढꡢҤ̳мΡOR˥եߥ꡼ȤơɡǴ̾ˤˤȯƤޤʤǶǤϡ̳мΡORˤϡ̾ʳ¡ȿˤ¸ߤֹδΤˤϴͿޤפ͡ǽ˴ͿƤȹͤƤޤܥǤ⡢㤨ư̮(2016-7-7)2015-6-8) (2015-2-25) (2015-1-18) (2014-6-4) (2013-12-18)ʤɤǤ¸ߤҲ𤷤Ƥޤ¡ʳˤ⡢̳мΤϡòɡǾ¡¡ա()()ʤɤ¸ߤ͡ǽ˴Ϳǽޤ


   ϡҥȤιº˦ˤϡ̳мΤOR2AT4OR51B5ȯƤꡢοǽ𤷤ɥĤθ楰ݥפΤҲǤ̳мOR2AT4ϡɽΥΥȡ˦ΥȤ¸ߤ뤳ȤΤƤꡢ륦åɡʥӥ㥯ˤ˧Ĺʪڥ󥿥Ρݥʥݥˤ礹뤳Ȥ⼨ƤޤΥȤϡOR51B5ȯƤꡢ˦ΰưˤϥ󥿡ݥ-6(IL-6)ʬˤطȹͤƤޤ


   ãϡҥº˦K562ӵ¡AMLˤ׾Ū˿Ǥ줿Ѥơž̥ݥ顼Ϣȿ(RT-PCR)Ӽ奷󥵡ݤˤä7̳мΡORˤ餫ˤޤǤ¿ȯƤΤϡOR2AT4OR51B5 OR52D1Ǥ


   ̳мOR2AT4˷礹륵ϡǥ˥顼åAMPϩ𤷤ơ륷।ήξ˦ϤͶƳޤOR2AT4Υ󥿥˥ȡɹˤǤե˥ݥ˧ޤϡͶȯκ˦⥫륷ή˳ޤݥˤ̳мΡOR2AT4ˤλɷϡº˦򸺾˥ޥåץʡݥΥ𤷤ƥݥȡʺ˦ˤͶȯ뤳Ȥ餫ˤޤ


   ޤϡº˦ʬͶƳⵯإ⥰ӥͭ˦οäޤΤ褦̳мΡORˤλɷˤꡢ˦ʬͶƳݥȡݥͶƳʤɤ뤳Ȥ˼ޤΥᥫ˥ʹʪ˦椹ˤϡ¡AMLˤμŤΤοˤʤǽԤޤ


   ˤҤ٤ޤ̳мΤϤȤʪγƼ˦˹ȯơѤôäƤΤʲβ̾˽󤵤졢δΤȤ̤οʵǽפΤ⤷ޤ Τ褦˹ʬҤǧ̳мΤϡפʤȤǡפʤƯ򤷤ƤǽޤޤȻפޤ (by Mashi)


ʸS Manteniotis et al., Functional characterization of the ectopically expressed olfactory receptor 2AT4 in human myelogenous leukemia. Cell Death Discovery 2 (2016), Article number: 15070  doi:10.1038/cddiscovery.2015.70
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