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ԥݤEB륹νʣϰߤȯɤιꥹ ҥå
2017-5-12 7:58 : Mashi () [ 626hit ]

   ߡߤŪˤ̤˴̤Ƥޤޤܤޤ쥢ϡߤιȯϰȤΤ졢ܤǤǯͤߤ˴ʤäƤޤܿͤΰߤʬϡԥݤȤʤȯɤȹͤƤޤԥݡʥإꥳХԥˤϡҥȤΰǴ¸ٶݤǤꡢǯʾܿͤ¿˴Ƥޤԥݤ³ϡ߱ʤӤ˰ʤɤΰǴѤߤȯɤδΨͭդ˹뤳ȤƤޤ


   Ȥǥ륹ȯΰĤθǤץ󡦥СEB˥륹ϡB ˦ΰǤСåȥѼۥѼθȤʤꡢޤɡƬͶȯȹͤƤޤEB륹ϡB ˦˴إڥ륹Ǥꡢ¿ηͤB ˦ƤޤEB 륹¾˦ؤδ̤ʬ˲Ƥޤ󤬡EB 륹B ˦Ⱦ˦ľŪܿ˽פôȹͤƤޤߤˤƤϡ10%ξˤƤ˦ðŪEB 륹Ƥ뤳ȤΤƤޤ


   ñ˹ͤƤ⡢ȯˤĤʤٶݡʥԥݡˤȥ륹EB륹ˤˤʤȯ٤Ϲ⤯ʤǤޤԥݤEB륹ζߤȯɤ˵ڤܤϤޤ椵ƤޤǤǶررθãߤȯɤˤԥݤEB륹ϢȤޤ̤ϡȯٶݤȯ󥦥륹ϢȤƥҥȤΤȯɤ¥Ȥߤǽ餫ˤŪʸȤޤ


   ԥݤϰߤκ˦ɽ̤夷塢ݤͭߥͿˤѤƥԥݥѥCagA ˦ľޤCagAѥϰ߾˦˿塢Ȥ뤳Ȥȯȯޤãϡ줿ԥݥѥCagAΥ򳰤æ˹SHP1餫ˤޤSHP1ˤæѤη̡CagAѥȯ㲼뤳Ȥ顢SHP1ϰߤȯɤʬҤȹͤޤФEB륹ߤκ˦ǤSHP1ȯ졢줿ԥCagAѥȯϡ뤳Ȥ餫ˤʤޤΤ褦ʻȤߤˤꡢߤȯɤˤȯٶݤȯ󥦥륹ϢȤȯˤĤʤäƤȻפޤ


   ĿͤθۤǤޤ30ǯʾзȼ򤯤֤ˤ˰ΤäˤʤäƤޤǯΰ򵡤ˡǥԥݤνݤ򤷤ޤ衢Τäˤʤ餺ݥҡݤ褦ˤʤꡢȯɤƤޤ󡣲Τˤϼ夯ʤޤ(by Mashi)


ʸPriya Saju et al., Host SHP1 phosphatase antagonizes Helicobacter pylori CagA and can be downregulated by Epstein-Barr virus. Nature Microbiology, DOI: 10.1038/nmicrobiol.2016.26.  
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