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2015-2-25 10:01 : Mashi () [ 6660hit ]

   Υ(2015-1-18)ǡκ˦ʥΥȡˤ̳м(OR2AT4)Ĥꡢ̳мΤ˥륦åɡʥӥ㥯ͤ˧Ჽʪڥ󥿥Ρݥ뤬礷ͶƳ뤳ȤҲ𤷤ޤϡҥȴ¡κ˦˴Ϣ̳м(OR1A2)˸ĤäȤ򤴾Ҳ𤷤ޤ

   ȥͥݥC10H19OHϡΥƥڥ󥢥륳ݥʿ޻ȡˤǤꡢ˥ࡢȥͥ顢ݥꡦȥꥪɥʥݥˤʤɤ˴ޤޤƤޤȥͥݥC9H17CHOϡΥƥڥ󥢥ǥҥʿ޻ȡˤǤꡢ󥰥饹åȥͥ顢ݥꡦȥꥪɥʥݥˤʤɤ˴ޤޤƤޤΥޤϡǤޤȤƤȤƤޤҥȤˤϿϤ褤ȥ饹ϤιǤꡢФ塢եݥķϤΥեݥСݤʤɤ˹ѤƤޤ

   Ρʤ˺˦ˤΥޤФ̳мΤ¸ߤƤ뤳ȤɥĤθݥˤ꿷𤵤ޤãϥҥȴΤ˦ǥѤ11Υƥڥ˦˺ѤȤȥͥ顼ȥȥͥĤ˦Υ륷ǻ٤äȤ򸫤Ĥޤ˥ȥͥ顼˾Ĵ٤Ȥ̳мOR1A2Τ˦ɽ̤¸ߤƤơȥͥ顼θΤӺ˦ȿ˴ͿƤ뤳Ȥ򸫤ޤޤ̳мΤ˦ȡƥڥȿʤʤޤ

   ƥڥ󤬺˦ǥ륷ǻ٤ä˦륷ʥãϩɷ㤹뤳Ȥ顢ݥϡ̳мOR1A2ϴΤ˦ǽפʬҤǤꡢŪˤϡ̳мΤ¡οǤӼŤΤɸŪʬҤˤʤǽ仡ƤޤޤϡɡʳǤ̳мΤν򼨤ǤꡢƤѤʤγȯβǽפȤҤ٤Ƥޤ

   ҥȤ400ढ̳мΤΰĤǤOR1A2ϡ쾮Ĥ˸ĤäƤꡢޤ¡κ˦ˤ鷺ʤ鸡ФƤޤʸϤ褯ʬޤ󤬡Τ˦ǤϤ̳мΤ¿̤ȯƤꡢƥڥ˸Ψ褯ȿƤΤΤޤ󡣴Τ˦κ˦ǤΡ̳мΤμŪŪʰ㤤θƤϺפʲȻפޤ

   ˤ衢Τ褦ˡ¤ΤΤκ˦̳мΤμƤˤľܴͿƤޤ󤬡͡ˤʤäƤǽȻפޤ(by Mashi)



ʸDésirée Maßberga, et al., Monoterpene (−)-citronellal affects hepatocarcinoma cell signaling via an olfactory receptor. Archives of Biochemistry and Biophysics. Volume 566, 15 January 2015, Pages 100–109.
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